A flexible option, you can hop off the bus at any designated stop and simply hop back onto the next bus. Passing by key attractions like the Colosseum, Vatican City, Spanish Steps, and Pantheon, common ticket choices include the 24-hour, 48-hour, or 72-hour passes. Typically operating on continuous loops, a Rome Hop-on Hop-off bus tour full circuit can take about 1.5 to 2 hours.