- Historical significance: Built over the ruins of three Roman temples (3rd–2nd centuries BCE) near the Forum Olitorium, it reflects a rich history tied to ancient Rome and a tradition of a medieval prison on the site.
- Art and architecture: Features a three-nave layout with 14 columns from ancient temples, rebuilt in the 16th century by Giacomo Della Porta and restored in the 19th century. Inside are notable works by Guercino and Antonio Romano.
- Current use: Serves as a minor basilica and local place of worship, particularly for communities from Puglia and Lucania, while drawing visitors interested in its history and architecture.
- Accessibility: Lacks wheelchair accessibility, posing challenges for visitors with mobility issues.
- Key features: Highlights include the incorporation of ancient temple remains, Renaissance frescoes, a unique façade blending medieval and Renaissance elements, and an underground area showcasing Rome's layered history.